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Bim [SU0318] Antibody

CAT: 1071-OM637218-01Size: 100 µLDry Ice: NoHazardous: No
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CAT#:1071-OM637218-01Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pro-apototic Bcl-2 family members promote cell death by neutralizing their anti-apoptotic relatives, which otherwise maintain cell viability by regulating caspase activity. Bim belongs to the BH3-only subgroup of Bcl-2 related proteins, and exists in three distinct isoforms, BimS (short), BimL (long) and BimEL (extra long) . ERK1/2 phosphorylates BimEL, resulting in rapid degradation of the isoform via the proteasome pathway. At least three sites for ERK1/2 phosphorylation exist on BimEL, whereas ERK1/2 does not effect BimS and BimL, implying a unique role for BimEL in cell survival signaling.
Immunogen
Recombinant protein
Antibody Type
Primary Antibodies
Product Name Synonym
BCL2 like 11 antibody B2L11_HUMAN antibody BAM antibody Bcl 2 interacting protein Bim antibody Bcl 2 related ovarian death agonist antibody Bcl-2-like protein 11 antibody BCL2 interacting mediator of cell death antibody BCL2 like 11 (apoptosis facilitator) antibody BCL2 like protein 11 antibody Bcl2-interacting mediator of cell death antibody Bcl2-L-11 antibody Bcl2l11 antibody BIM alpha6 antibody BIM antibody BIM beta6 antibody BIM beta7 antibody BimEL antibody BimL antibody BOD antibody

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