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Artn Antibody

CAT: 1071-OM636884-01Size: 100 µLDry Ice: NoHazardous: No
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CAT#:1071-OM636884-01Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene encodes a secreted ligand of the glial cell line-derived neurotrophic factor (GDNF) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein signals through the RET receptor and GFR alpha 3 coreceptor, and supports the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. This protein has also been shown to promote tumor growth, metastasis, and drug resistance in mammary carcinoma.
Immunogen
Synthetic peptide from human protein at AA range: 101-150
Antibody Type
Primary Antibodies
Product Name Synonym
Artemin (Enovin) (Neublastin) antibody

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