Products for Research Use Only

ASAH3 Antibody

CAT: 1071-OM636760-01Size: 100 µLDry Ice: NoHazardous: No
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CAT#:1071-OM636760-01Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ceramides are synthesized during epidermal differentiation and accumulate within the interstices of the stratum corneum, where they represent critical components of the epidermal permeability barrier. Excess cellular ceramide can trigger antimitogenic signals and induce apoptosis, and the ceramide metabolites sphingosine and sphingosine-1-phosphate (S1P) are important bioregulatory molecules. Ceramide hydrolysis in the nucleated cell layers regulates keratinocyte proliferation and apoptosis in response to external stress. Ceramide hydrolysis also occurs at the stratum corneum, releasing free sphingoid base that functions as an endogenous antimicrobial agent. ACER1 is highly expressed in epidermis and catalyzes the hydrolysis of very long chain ceramides to generate sphingosine (Houben et al. 2006
Immunogen
Synthesized peptide derived from ASAH3 . at AA range: 100-180
Antibody Type
Primary Antibodies
Product Name Synonym
ACER1 antibody; ASAH3 antibody; Alkaline ceramidase 1 antibody; AlkCDase 1 antibody; Alkaline CDase 1 antibody; Acylsphingosine deacylase 3 antibody; N-acylsphingosine amidohydrolase 3 antibody