CD42d Antibody

• Description:

  Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9; MIM 173515) and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200), a bleeding disorder (review by Lopez et al. 1998

• Immunogen:

  The antiserum was produced against synthesized peptide derived from the Internal region of human GP5. AA range:331-380

• Antibody Type:

  Primary Antibodies

• Product Name Synonym:

  GP5 antibody; Platelet glycoprotein V antibody; GPV antibody; Glycoprotein 5 antibody; CD42d antibody