Integrin α4 Antibody

• Description:

  The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants.

• Immunogen:

  The antiserum was produced against synthesized peptide derived from the Internal region of human ITGA4. AA range:571-620

• Antibody Type:

  Primary Antibodies

• Product Name Synonym:

  ITGA4 antibody; CD49D antibody; Integrin alpha-4 antibody; CD49 antigen-like family member D antibody; Integrin alpha-IV antibody; VLA-4 subunit alpha antibody; CD49d antibody