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Zhangfei Antibody

CAT: 1071-OM636426-01Size: 100 µLDry Ice: NoHazardous: No
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CAT#:1071-OM636426-01Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. Able to down-regulate expression of some cellular genes in CREBZF-expressing cells. miscellaneous:Named Zhangfei after a legendary Chinese warrior who was contemporary with Luman in around 220 AD. Belongs to the bZIP family. ATF subfamily. Contains 1 bZIP domain. subcellular location:Colocalizes at punctate nuclear structures with CREB3 and HCFC1. subunit:Interacts with HCFC1, causing suppression of CREB3 transcriptional activity. tissue specificity:In adults, expressed most abundantly in heart, liver and skeletal muscle, moderately abundant in kidney and pancreas, and barely detectable in lungs. In fetal tissues, expressed most abundantly in kidney and very low amounts in heart, lung and liver.
Immunogen
The antiserum was produced against synthesized peptide derived from human CREBZF. AA range:221-270
Antibody Type
Primary Antibodies
Product Name Synonym
CREBZF antibody; ZF antibody; CREB/ATF bZIP transcription factor antibody; Host cell factor-binding transcription factor Zhangfei antibody; HCF-binding transcription factor Zhangfei antibody

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