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XPG Antibody

CAT: 1071-OM636411-01Size: 100 µLDry Ice: NoHazardous: No
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CAT#:1071-OM636411-01Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic, immunoglobulin-like variable motif containing) gene.
Immunogen
The antiserum was produced against synthesized peptide derived from human ERCC5. AA range:131-180
Antibody Type
Primary Antibodies
Product Name Synonym
ERCC5 antibody; ERCM2 antibody; XPG antibody; XPGC antibody; DNA repair protein complementing XP-G cells antibody; DNA excision repair protein ERCC-5 antibody; Xeroderma pigmentosum group G-complementing protein antibody

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