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XIAP Antibody

CAT: 1071-OM636409-01Size: 100 µLDry Ice: NoHazardous: No
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CAT#:1071-OM636409-01Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.
Immunogen
The antiserum was produced against synthesized peptide derived from human XIAP. AA range:53-102
Antibody Type
Primary Antibodies
Product Name Synonym
XIAP antibody; API3 antibody; BIRC4 antibody; IAP3 antibody; E3 ubiquitin-protein ligase XIAP antibody; Baculoviral IAP repeat-containing protein 4 antibody; IAP-like protein antibody; ILP antibody; hILP antibody; Inhibitor of apoptosis protein 3 antibody; IAP-3 antibody; hIAP-3 antibody; hIAP3 antibody; X-linked inhibitor of apoptosis protein antibody; X-linked I antibody

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