VPS72 Antibody

• Description:

  The protein encoded by this gene is a shared subunit of two multi-component complexes, the histone acetyltransferase complex TRRAP/TIP60 as well as the chromatin remodeling SRCAP-containing complex. The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation, double strand DNA break repair and apoptosis. The SRCAP-containing complex catalyzes the exchange of histone H2A with the histone variant Htz1 (H2AFZ) into nucleosomes. This protein may be responsible for binding H2AFZ, which has a role in chromosome segregation. This protein may also have a role in regulating long-term hematopoietic stem cell activity. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human VPS72. AA range:131-180

• Antibody Type:

  Primary Antibodies

• Product Name Synonym:

  VPS72 antibody; TCFL1 antibody; YL1 antibody; Vacuolar protein sorting-associated protein 72 homolog antibody; Protein YL-1 antibody; Transcription factor-like 1 antibody