TWEAK Antibody

• Description:

  The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13.

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human TNFSF12. AA range:41-90

• Antibody Type:

  Primary Antibodies

• Product Name Synonym:

  TNFSF12 antibody; APO3L antibody; DR3LG antibody; Tumor necrosis factor ligand superfamily member 12 antibody; APO3 ligand antibody; TNF-related weak inducer of apoptosis antibody; TWEAK antibody