TRADD Antibody

• Description :

  The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway.

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human TRADD. AA range:251-300

• Antibody Type :

  Primary Antibodies

• Product Name Synonym :

  TRADD antibody; Tumor necrosis factor receptor type 1-associated DEATH domain protein antibody; TNFR1-associated DEATH domain protein antibody; TNFRSF1A-associated via death domain antibody