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TIRAP Antibody

CAT: 1071-OM636262-01Size: 100 µLDry Ice: NoHazardous: No
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CAT#:1071-OM636262-01Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described.
Immunogen
The antiserum was produced against synthesized peptide derived from human TIRAP. AA range:52-101
Antibody Type
Primary Antibodies
Product Name Synonym
TIRAP antibody; MAL antibody; Toll/interleukin-1 receptor domain-containing adapter protein antibody; TIR domain-containing adapter protein antibody; Adaptor protein Wyatt antibody; MyD88 adapter-like protein antibody

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