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Smad2/3 Antibody

CAT: 1071-OM636070-01Size: 100 µLDry Ice: NoHazardous: No
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CAT#:1071-OM636070-01Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF) -beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation
Immunogen
The antiserum was produced against synthesized peptide derived from human Smad2/3. AA range:1-50
Antibody Type
Primary Antibodies
Product Name Synonym
SMAD2 antibody; MADH2 antibody; MADR2 antibody; Mothers against decapentaplegic homolog 2 antibody; MAD homolog 2 antibody; Mothers against DPP homolog 2 antibody; JV18-1 antibody; Mad-related protein 2 antibody; hMAD-2 antibody; SMAD family member 2 antibody; SMAD 2 antibody; Smad2 antibody; hSMAD2 antibody; SMAD3 antibody; MADH3 antibody; Mothers against decapentaplegic antibody

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