SETMAR Antibody

• Description:

  This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human SETMAR. AA range:350-400

• Antibody Type:

  Primary Antibodies

• Product Name Synonym:

  SETMAR antibody; Histone-lysine N-methyltransferase SETMAR antibody; SET domain and mariner transposase fusion gene-containing protein antibody; HsMar1 antibody; Metnase antibody