PP2Cε Antibody

• Description:

  The protein encoded by this gene is a magnesium or manganese-requiring phosphatase that is involved in several signaling pathways. The encoded protein downregulates apoptosis signal-regulating kinase 1, a protein that initiates a signaling cascade that leads to apoptosis when cells are subjected to cytotoxic stresses. This protein also is an endoplasmic reticulum transmembrane protein that helps regulate ceramide transport from the endoplasmic reticulum to the Golgi apparatus. Finally, this gene may be involved in adiposity since it is upregulated in adipose tissues. Several transcript variants encoding different isoforms have been found for this gene.

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human PPM1L. AA range:119-168

• Antibody Type:

  Primary Antibodies

• Product Name Synonym:

  PPM1L antibody; PP2CE antibody; Protein phosphatase 1L antibody; Protein phosphatase 1-like antibody; Protein phosphatase 2C isoform epsilon antibody; PP2C-epsilon antibody