PCB Antibody

• Description :

  This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human PC. AA range:357-406

• Antibody Type :

  Primary Antibodies

• Product Name Synonym :

  PC antibody; Pyruvate carboxylase antibody; mitochondrial antibody; Pyruvic carboxylase antibody; PCB antibody