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Patched Antibody

CAT: 1071-OM635615-01Size: 100 µLDry Ice: NoHazardous: No
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CAT#:1071-OM635615-01Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently.
Immunogen
The antiserum was produced against synthesized peptide derived from human Patched. AA range:1-50
Antibody Type
Primary Antibodies
Product Name Synonym
PTCH1 antibody; PTCH antibody; Protein patched homolog 1 antibody; PTC antibody; PTC1 antibody