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P18 Antibody

CAT: 1071-OM635581-01Size: 100 µLDry Ice: NoHazardous: No
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CAT#:1071-OM635581-01Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported.
Immunogen
The antiserum was produced against synthesized peptide derived from human p18 INK. AA range:111-160
Antibody Type
Primary Antibodies
Product Name Synonym
CDKN2C antibody; CDKN6 antibody; Cyclin-dependent kinase 4 inhibitor C antibody; Cyclin-dependent kinase 6 inhibitor antibody; p18-INK4c antibody; p18-INK6 antibody

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