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P15 Antibody

CAT: 1071-OM635579-01Size: 100 µLDry Ice: NoHazardous: No
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CAT#:1071-OM635579-01Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.
Immunogen
The antiserum was produced against synthesized peptide derived from human p15 INK. AA range:89-138
Antibody Type
Primary Antibodies
Product Name Synonym
CDKN2B antibody; MTS2 antibody; Cyclin-dependent kinase 4 inhibitor B antibody; Multiple tumor suppressor 2 antibody; MTS-2 antibody; p14-INK4b antibody; p15-INK4b antibody; p15INK4B antibody

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