Recombinant UBE2S Protein

• Description:

  Recombinant UBE2S Protein_x000D_ Catalog number: B2017698_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 50 µg_x000D_ Molecular Weight or Concentration: 26.01 kDa_x000D_ Supplied as: Solution_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -80°C_x000D_ Keywords: Ubiquitin conjugating enzyme E2 S, E2-EPF, E2EPF, EPF5_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Paul A, Wang B. RNF8- and Ube2S-Dependent Ubiquitin Lysine 11-Linkage Modification in Response to DNA Damage Mol Cell. 2017 May 18;66(4):458-472.e5._x000D_ 2: Bremm A, Komander D. Synthesis and analysis of K11-linked ubiquitin chains Methods Mol Biol. 2012;832:219-28._x000D_ 3: Zhang S, Shen Y, Li H, Bi C, Sun Y, Xiong X, Wei W, Sun Y. The Negative Cross-Talk between SAG/RBX2/ROC2 and APC/C E3 Ligases in Regulation of Cell Cycle Progression and Drug Resistance Cell Rep. 2020 Sep 8;32(10):108102._x000D_ 4: Gui L, Zhang S, Xu Y, Zhang H, Zhu Y, Kong L. UBE2S promotes cell chemoresistance through PTEN-AKT signaling in hepatocellular carcinoma Cell Death Discov. 2021 Nov 16;7(1):357._x000D_ 5: Tang H, Fang T, Ji M, Wang JP, Song LL, Zhang QY, Wu JS. UBE2S exerts oncogenic activities in urinary bladder cancer by ubiquitinating TSC1 Biochem Biophys Res Commun. 2021 Nov 12;578:7-14._x000D_ 6: Zhang M, Wang J, Guo Y, Yue H, Zhang L. Activation of PI3K/AKT/mTOR signaling axis by UBE2S inhibits autophagy leading to cisplatin resistance in ovarian cancer J Ovarian Res. 2023 Dec 19;16(1):240._x000D_ 7: Liu Z, Xu L. UBE2S promotes the proliferation and survival of human lung adenocarcinoma cells BMB Rep. 2018 Dec;51(12):642-647._x000D_ 8: Zhang R, Li C, Zhang S, Kong L, Liu Z, Guo Y, Sun Y, Zhang C, Yong Y, Lv J, Lu M, Liu M, Wu D, Zhang T, Yang H, Wei D, Chen Z, Bian H. UBE2S promotes glycolysis in hepatocellular carcinoma by enhancing E3 enzyme-independent polyubiquitination of VHL Clin Mol Hepatol. 2024 Jun 25._x000D_ 9: Sun SM, Zhao BW, Li YY, Liu HY, Xu YH, Yang XM, Guo JN, Ouyang YC, Weng CJ, Guan YC, Sun QY, Wang ZB. Loss of UBE2S causes meiosis I arrest with normal spindle assembly checkpoint dynamics in mouse oocytes Development. 2024 Mar 15;151(6):dev202285._x000D_ 10: Lin M, Lei T, Zheng J, Chen S, Du L, Xie H. UBE2S mediates tumor progression via SOX6/β-Catenin signaling in endometrial cancer Int J Biochem Cell Biol. 2019 Apr;109:17-22. _x000D_ _x000D_ Products Related to Recombinant UBE2S Protein can be found at Proteins

• Short Description:

  Catalog Number: B2017698 (50 µg)_x000D_ Recombinant UBE2S protein is a version of the UBE2S protein that is produced using recombinant DNA technology. UBE2S is an enzyme that plays a role in the ubiquitination pathway, which is a process that marks proteins for degradation. Recombinant UBE2S protein can be used in research studies to investigate its function and interactions with other proteins. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3