RegisterLogin

Grb2 Antibody

CAT: 0498-bsm-70510MSize: 100 µLDry Ice: NoHazardous: No
CAT#: bsm-70510MSize: 100 µL
Selected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Crk and Grb2 family adaptor proteins are involved in a variety of cell signaling pathways related to human diseases. These adaptors have Src homology 2 (SH2) and Src homology 3 (SH3) domains, which are docking sites for several signaling proteins, including receptors, kinases, and GTPase regulators. In addItion, other protein-protein interactions may also utilize Crk and Grb2 domain interactions to modulate cell signaling pathways. The DOCK family of proteins (DOCK3, DOCK4, and DOCK5) can interact with Crk and may be important Crk effector proteins. The cell cycle regulator p27Kip1 can interact with Grb2, and this implicates Grb2 activity in cell signaling pathways that alter cell cycle progression.
Synonyms
Grb
Swiss Prot
P62994
Host
Mouse
Cross Reactivity
Human, Mouse, Rat
Target
Grb2
Clonality
Monoclonal
Isotype
IgG1
Clone
M331
Conjugation
Unconjugated
Source
Clone (M331) was generated from a full length recombinant rat Grb2 protein. This sequence has high homology to human and mouse Grb2.
Applications
WB, IP
Purification
Purified by Protein A.
Dilution
WB (1:300-5000), IP (1-2ug)
Buffer
PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol
Modification
Unmodified
Storage Conditions
Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
Specificity
This antibody detects a 24 kDa* protein corresponding to the molecular mass of Grb2 on SDS-PAGE immunoblots of rat PC12.

Related Products

CatalogName
bsm-62088R-TRGRB2 Recombinant Antibody
bs-1465RGRB2 Polyclonal Antibody
bsm-62088R-01GRB2 Recombinant Antibody
bsm-62088R-Cy5-01GRB2 Recombinant Antibody, Cy5 Conjugated
bsm-62088R-Cy7-01GRB2 Recombinant Antibody, Cy7 Conjugated
bs-1465R-APCGRB2 Polyclonal Antibody, APC Conjugated
bs-1465R-PEGRB2 Polyclonal Antibody, PE Conjugated
bs-1465R-RBITCGRB2 Polyclonal Antibody, RBITC Conjugated
bsm-62088R-PerCP-01GRB2 Recombinant Antibody, PerCP Conjugated
bs-1465R-Cy3GRB2 Polyclonal Antibody, Cy3 Conjugated

Alternative Products

CatalogName
MBS7123748-01GRB2 Antibody
MBS9435420-01GRB2 Antibody
MBS9410458-01GRB2 Antibody
F49558-0.4MLGRB2 Antibody
R35139-100UGGRB2 Antibody
MBS2529665-01GRB2 Antibody
MBS9416038-01GRB2 Antibody
MBS9215520-01GRB2 Antibody
N0861-01GRB2 Antibody
KC-6288-01GRB2 Antibody

Popular Products