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Recombinant Human PAICS

CAT: 0710-P4925-01Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0710-P4925-01Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
ADE2, ADE2H1, AIR carboxylase, AIRC, DKFZp781N1372, MGC1343, MGC5024, Multifunctional protein ADE2, Multifunctional protein ADE2H1, Paics, PAIS, Phosphoribosylaminoimidazole carboxylase, Phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase, PUR6_HUMAN, SAICAR synthetase
UniProt
P22234
Expression Region
1-425
Host
E.Coli
Tag
N-terminal His Tag or N-terminal His-IF2DI Tag, determined during production process
Applications
Western Blot, ELISA
Field of Research
Metabolism
Purity
Greater than 90% as determined by SDS-PAGE.
Form
Lyophilized powder
Reconstitution
Centrifuge the vial before opening, reconstitute in sterile distilled water to a concentration of 0.1-1 mg/ml by gently pipetting 2-3 times, don't vortex.
Molecular Weight
46.6 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
The lyophilized protein is stable at -20 °C for up to 1 year. For extended storage, it is recommended to further dilute in working aliquots after reconstitution. The protein solution is stable at ≤ -20 °C for 3 months, or 2-7 days at 2-8 °C under sterile conditions.Avoid repeated freeze/thaw cycle.
Formulation
Lyophilized from a 0.2 μm filtered solution of 10 mM Hepes, 150 mM NaCl with 5% trehalose, pH 7.4.
Organism Species
Human

UniProtKB · P22234

Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

PUR6_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P22234
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PAICS
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
PAICS
EC number
—
Processing
—
Secondary accessions
E9PDH9, Q68CQ5
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Molecular function

DecarboxylaseLigaseLyaseMultifunctional enzyme

Disease

Disease variant

Biological process

Purine biosynthesis

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