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Olvanil

CAT: 0804-HY-101323-06Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-101323-06Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Olvanil (NE-19550) is an analgesic and an agonist of transient receptor potential vanilloid type 1 (TRPV1) channels with an EC50 of 0.7 nM[1].
CAS Number
58493-49-5
Product Name Alternative
NE-19550; N-Vanillyloleamide
UNSPSC
12352005
Hazard Statement
H225, H319
Target
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/olvanil.html
Purity
99.0
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CCCCCCCC/C=C\CCCCCCCC(NCC1=CC=C(O)C(OC)=C1)=O
Molecular Formula
C26H43NO3
Molecular Weight
417.62
Precautions
H225, H319
References & Citations
[1]Giovanni Appendino, et al. Development of the first ultra-potent "capsaicinoid" agonist at transient receptor potential vanilloid type 1 (TRPV1) channels and its therapeutic potential. J Pharmacol Exp Ther. 2005 Feb;312 (2) :561-70.|[2]S O Jacobsson, et al. Inhibition of rat C6 glioma cell proliferation by endogenous and synthetic cannabinoids. Relative involvement of cannabinoid and vanilloid receptors.J Pharmacol Exp Ther. 2001 Dec;299 (3) :951-9.|[3]John W Kasckow, et al. Effects of the vanilloid agonist olvanil and antagonist capsazepine on rat behaviors. Prog Neuropsychopharmacol Biol Psychiatry. 2004 Mar;28 (2) :291-5.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TRPV1

Chemical Information

Olvanil

N-Vanillyloleamide is a member of phenols and a member of methoxybenzenes.

CAS Number58493-49-5
PubChem CID5311093
IUPAC Name(Z)-N-[(4-hydroxy-3-methoxyphenyl)methyl]octadec-9-enamide
Molecular FormulaC26H43NO3
Molecular Weight417.6
XLogP8.1
Topological Polar Surface Area58.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count18
Heavy Atom Count30
Formal Charge0
Complexity438
SMILES
CCCCCCCC/C=C\CCCCCCCC(=O)NCC1=CC(=C(C=C1)O)OC
InChI
InChI=1S/C26H43NO3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-26(29)27-22-23-19-20-24(28)25(21-23)30-2/h10-11,19-21,28H,3-9,12-18,22H2,1-2H3,(H,27,29)/b11-10-
InChIKey
OPZKBPQVWDSATI-KHPPLWFESA-N
Chemical Structure
2D Structure
2D structure of Olvanil
CAS: 58493-49-5
CID: 5311093
Formula: C26H43NO3
MW: 417.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight417.6
XLogP38.1
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count18
Exact Mass417.32429423
Monoisotopic Mass417.32429423
Topological Polar Surface Area58.6 Ų
Heavy Atom Count30
Formal Charge0
Complexity438
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
B6512-50Olvanil
TBI4491-25MGOlvanil, TRPV1 agonist

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