Caspase 2 Recombinant Antibody, Cy3 Conjugated

• Background:

  Caspase-2 is a Class I caspase with a long prodomain necessary for nuclear localization. Caspase-2 is the nuclear apoptotic respondent to cellular genotoxic stress or mitotic catastrophe. Activation occurs upon recruitment to a complex containing a p53-induced death domain protein, PIDD.

• Synonyms:

  Caspase-2; Caspase 2; Caspase2; CASP-2; Neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2; Protease ICH-1; CASP2; ICH1; NEDD2.

• Gene ID:

  835

• Swiss Prot:

  P42575

• Cellular Locus:

  Cytoplasm, Nucleus

• Host:

  Rabbit

• Cross Reactivity:

  Human, Mouse, Rat

• Target:

  Caspase 2

• Clonality:

  Recombinant

• Isotype:

  IgG

• Conjugation:

  Cy3

• Source:

  KLH conjugated synthetic peptide derived from human Caspase 2

• Applications:

  WB, IF, Flow-Cyt

• Purification:

  Purified by Protein A.

• Excitation Emission:

  512,550nm/570,615nm

• Concentration:

  Lot dependent

• Dilution:

  WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)

• Buffer:

  Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification:

  Unmodified

• Storage Conditions:

  Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

• Gene ID URL:

  835