Arylomycin A2

• Description :

  Arylomycin A2, an antibiotic (Antibiotic), is a lipopeptide type I signal peptidase (SPase I) inhibitor. Arylomycin A2 has antibacterial effects[1].

• UNSPSC :

  12352209

• Target :

  Antibiotic; Bacterial

• Type :

  Peptides

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/arylomycin-a2.html

• Purity :

  97.37

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C([C@H]1NC([C@H](C)NC([C@@H](N(C)C(CNC([C@@H](C)NC([C@@H](CO)N(C)C(CCCCCCCCC(C)C)=O)=O)=O)=O)C2=CC=C(C(C3=CC(C1)=CC=C3O)=C2)O)=O)=O)O

• Molecular Formula :

  C42H60N6O11

• Molecular Weight :

  824.96

• References & Citations :

  [1]Mark Paetzel, et al. Crystallographic and biophysical analysis of a bacterial signal peptidase in complex with a lipopeptide-based inhibitor. J Biol Chem. 2004 Jul 16;279 (29) :30781-90. |[2]Katrijn Bockstael, et al. Evaluation of the type I signal peptidase as antibacterial target for biofilm-associated infections of Staphylococcus epidermidis. Microbiology (Reading) . 2009 Nov;155 (Pt 11) :3719-3729.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported

• Isoform :

  Lipopeptide

• CAS Number :

  [459844-20-3]