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Arylomycin A2

CAT: 0804-HY-P3884-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P3884-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Arylomycin A2, an antibiotic (Antibiotic), is a lipopeptide type I signal peptidase (SPase I) inhibitor. Arylomycin A2 has antibacterial effects[1].
CAS Number
459844-20-3
UNSPSC
12352209
Target
Antibiotic; Bacterial
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/arylomycin-a2.html
Purity
97.37
Solubility
10 mM in DMSO
Smiles
O=C([C@H]1NC([C@H](C)NC([C@@H](N(C)C(CNC([C@@H](C)NC([C@@H](CO)N(C)C(CCCCCCCCC(C)C)=O)=O)=O)=O)C2=CC=C(C(C3=CC(C1)=CC=C3O)=C2)O)=O)=O)O
Molecular Formula
C42H60N6O11
Molecular Weight
824.96
References & Citations
[1]Mark Paetzel, et al. Crystallographic and biophysical analysis of a bacterial signal peptidase in complex with a lipopeptide-based inhibitor. J Biol Chem. 2004 Jul 16;279 (29) :30781-90. |[2]Katrijn Bockstael, et al. Evaluation of the type I signal peptidase as antibacterial target for biofilm-associated infections of Staphylococcus epidermidis. Microbiology (Reading) . 2009 Nov;155 (Pt 11) :3719-3729.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
Lipopeptide

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