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BRCA2 Monoclonal Antibody

CAT: 0498-bsm-51693MSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0498-bsm-51693MSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA (ssDNA) . Acts by targeting RAD51 to ssDNA over double-stranded DNA, enabling RAD51 to displace replication protein-A (RPA) from ssDNA and stabilizing RAD51-ssDNA filaments by blocking ATP hydrolysis. May participate in S phase checkpoint activation. Binds selectively to ssDNA, and to ssDNA in tailed duplexes and replication fork structures. In concert with NPM1, regulates centrosome duplication.
Synonyms
BRCA 2; BRCA1/BRCA2 containing complex subunit 2; BRCC 2; BRCC2; Breast and ovarian cancer susceptibility gene early onset; Breast cancer 2 early onset; Breast Cancer 2 tumor suppressor; Breast cancer susceptibility protein BRCA2; Breast cancer type 2 susceptibility protein; FACD; FAD 1; FAD; FAD1; FANCB; FANCD 1; FANCD; FANCD1; Fanconi anemia complementation group D1; Fanconi anemia group D1 protein; OTTHUMP00000018803; OTTHUMP00000042401; BRCA2_HUMAN.
Gene ID
675
Swiss Prot
P51587
Cellular Locus
Nucleus
Host
Mouse
Cross Reactivity
Recombinant protein
Target
BRCA2
Clonality
Monoclonal
Clone
F2H5
Conjugation
Unconjugated
Source
Recombinant human BRCA2_HUMAN.
Applications
WB
Concentration
0.5µg/µl
Dilution
WB (WB=1:500-2000)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
675
Predicted Cross Reactivity
Human

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