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SU1261

CAT: 0804-HY-169053-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-169053-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SU1261 is an IKK inhibitor with Ki values of 10 nM and 680 nM for IKKα and IKKβ, respectively. SU1261 can inhibit non-canonical NF-κB signaling in U2OS osteosarcoma cells[1].
CAS Number
3061890-98-7
UNSPSC
12352005
Target
IKK; NF-κB
Type
Reference compound
Related Pathways
NF-κB
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/su1261.html
Purity
99.13
Solubility
DMSO : ≥ 100 mg/mL
Smiles
NC1=NNC(C=C2)=C1C=C2C(C=CN=C3N4)=C3C=C4C5=CC=CC(OCC6=CC=CC=C6)=C5
Molecular Formula
C27H21N5O
Molecular Weight
431.49
References & Citations
[1]Riley C, et al. Design and Synthesis of Novel Aminoindazole-pyrrolo[2,3-b]pyridine Inhibitors of IKKα That Selectively Perturb Cellular Non-Canonical NF-κB Signalling. Molecules. 2024 Jul 26;29 (15) :3515.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IKK-α; IKK-β

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