DENND2C Polyclonal Antibody

• Background :

  DENND2C is a 928 amino acid protein that contains a dDENN domain, a DENN domain, and a uDENN domain and exists as three isoforms as a result of alternative splicing. The DENND2C protein is thought to target to actin filaments and control Rab9-dependent trafficking of mannose-6-phosphate receptor to lysosomes. The gene encoding DENND2C maps to human chromosome 1, the largest human chromosome which spans about 260 million base pairs and makes up 8% of the human genome. Other notable genes located on chromosome 1 include LMNA, which is associated with the rare aging disease Hutchinson-Gilford progeria, and the MUTYH gene, which is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome.

• Synonyms :

  DENN/MADD domain containing 2C; dJ1156J9.1; DKFZp686G0351; DKFZp686N1631; DKFZp779P1149; FLJ37099; RP5-1156J9.1; DEN2C_HUMAN.

• Gene ID :

  163259

• Host :

  Rabbit

• Cross Reactivity :

  Human

• Immunogen :

  231-330/928

• Target :

  DENND2C

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Conjugation :

  Unconjugated

• Source :

  KLH conjugated synthetic peptide derived from human DENND2C

• Applications :

  WB, IHC-P, IF (IHC-P)

• Purification :

  Purified by Protein A.

• Concentration :

  1µg/µl

• Dilution :

  WB (1:300-5000), IHC-P (1:200-400), IF (IHC-P) (1:50-200)

• Buffer :

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification :

  Unmodified

• Storage Conditions :

  Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

• Gene ID URL :

  163259

• Predicted Cross Reactivity :

  Mouse, Cow, Sheep, Horse, Rabbit