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FIGNL1 Polyclonal Antibody

CAT: 0498-bs-9433RSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0498-bs-9433RSize:100 µL
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Background
FIGNL1 is a 674 amino acid protein belonging to the AAA ATPase family. FIGNL1 exists as a hexamer that undergoes alternative splicing to produce two isoforms. FIGNL1 utilizes magnesium as a cofactor and is phosphorylated upon DNA damage, probably by ATM or ATR. FIGNL1 is suggested to regulate osteoblast proliferation and differentiation. FIGNL1 is encoded by a gene located on human chromosome 7, which consists about 158 milllion bases, encodes over 1000 genes and makes up about 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia.
Synonyms
Fidgetin like protein 1; fidgetin-like 1; FIGL1_HUMAN.
Gene ID
63979
Host
Rabbit
Cross Reactivity
Human
Immunogen
501-600/674
Target
FIGNL1
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human FIGNL1
Applications
WB, IHC-P, IF (IHC-P)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), IHC-P (1:200-400), IF (IHC-P) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
63979
Predicted Cross Reactivity
Mouse, Rat, Cow, Sheep, Pig, Horse, Chicken

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