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ANKRD17 Polyclonal Antibody

CAT: 0498-bs-9295RSize: 100 µLDry Ice: NoHazardous: No
CAT#:0498-bs-9295RSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ANKRD17 is a 2,603 amino acid protein that contains 25 ankyrin repeats and one KH domain. ANKRD17 is expressed in bone marrow and is thought to be involved in liver development. ANKRD17 localizes to the cytoplasm and the nucleus. ANKRD17 exists as five alternatively spliced isoforms that are encoded by a gene which maps to human chromosome 4. Representing approximately 6% of the human genome, chromosome 4 contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. Chromosome 4 reportedly contains the largest gene deserts (regions of the genome with no protein encoding genes) and has one of the two lowest recombination frequencies of the human chromosomes.
Synonyms
ANKRD 17; ANKRD-17; Ankyrin repeat domain protein 17; Ankyrin repeat domain-containing protein 17; ANR17_HUMAN; FLJ22206; Gene trap ankyrin repeat; Gene trap ankyrin repeat protein; GTAR; KIAA0697; NY BR 16; Serologically defined breast cancer antigen NY-BR-16
Gene ID
26057
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
1501-1600/2603
Target
ANKRD17
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human ANKRD17
Applications
ELISA, IHC-P, IHC-F, IF
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (ELISA=1:5000-10000), IHC-P (IHC-P=1:100-500), IHC-F (IHC-F=1:100-500), IF (IF=1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
26057

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