RegisterLogin

BAGE2 + BAGE3 Polyclonal Antibody

CAT: 0498-bs-9114RSize: 100 µLDry Ice: NoHazardous: No
CAT#:0498-bs-9114RSize:100 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements.Generally, BAGE proteins are silent in all normal tissues with the exception of testis. BAGE2 and BAGE 3 (B melanoma antigen 2 and 3, respectively), also known as Cancer/testis antigen 2.2 and 2.3 (respectively), are 109 amino acid secreted proteins that are expressed in 22% of melanomas, lung and bladder carcinomas, and are also expressed in normal testis tissue. Like the genes encoding MAGE proteins, BAGE genes are most likely silenced by DNA methylation and/or chromatin compaction in normal tissues other than testis.
Synonyms
B melanoma antigen 2; B melanoma antigen family, member 2; Cancer/testis antigen 2.2; CT2.2; BAGE2_HUMAN.
Host
Rabbit
Cross Reactivity
Human
Immunogen
55-109/109
Target
BAGE2 + BAGE3
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human BAGE2
Applications
ELISA, IHC-P, IHC-F, IF
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF ()
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Related Products

CatalogName
bs-9116RBAGE4 Polyclonal Antibody
bs-9116R-Cy3BAGE4 Polyclonal Antibody, Cy3 Conjugated
bs-9116R-FITCBAGE4 Polyclonal Antibody, FITC Conjugated
bs-9116R-HRPBAGE4 Polyclonal Antibody, HRP Conjugated
bs-9116R-RBITCBAGE4 Polyclonal Antibody, RBITC Conjugated
bs-9116R-BiotinBAGE4 Polyclonal Antibody, Biotin Conjugated
bs-9116R-Cy5BAGE4 Polyclonal Antibody, Cy5 Conjugated
bs-9116R-Cy7BAGE4 Polyclonal Antibody, Cy7 Conjugated
bs-9116R-PEBAGE4 Polyclonal Antibody, PE Conjugated
bs-9116R-PerCPBAGE4 Polyclonal Antibody, PerCP Conjugated

Alternative Products

CatalogName
MBS9238721-01BAGE2 + BAGE3 Polyclonal Antibody
SL9114R-01Rabbit Anti-BAGE2 + BAGE3 antibody
BT-AP00823-01BAGE3 Polyclonal Antibody
MBS2561499-01BAGE2 Polyclonal Antibody
E47R9114BAGE2 + BAGE3 Rabbit pAb

Popular Products