Hemoglobin Beta Polyclonal Antibody

• Background :

  The delta (HBD) and beta (HBB) genes are normally expressed in the adult: two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin. Two alpha chains plus two delta chains constitute HbA-2, which with HbF comprises the remaining 3% of adult hemoglobin. Five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon--Ggamma--Agamma--delta--beta-3'. Mutations in the delta-globin gene are associated with beta-thalassemia.

• Synonyms :

  CD113t-C; beta-globin; Hemoglobin subunit beta; Hemoglobin beta chain; HBB; Hemoglobin subunit delta; HBD; Delta-globin; Hemoglobin delta chain

• Gene ID :

  3043; 3045

• Swiss Prot :

  P68871; P02042

• Cellular Locus :

  Cytoplasm, Secreted

• Host :

  Rabbit

• Cross Reactivity :

  Human

• Immunogen :

  51-147/147

• Target :

  Hemoglobin Beta

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Conjugation :

  Unconjugated

• Source :

  KLH conjugated synthetic peptide derived from human Hemoglobin beta

• Applications :

  WB, ELISA

• Purification :

  Purified by Protein A.

• Concentration :

  1µg/µl

• Dilution :

  WB (1:300-5000), ELISA (1:500-1000)

• Buffer :

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification :

  Unmodified

• Storage Conditions :

  Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

• Specificity :

  Antibody has equal affinity for Human Hemoglobin Beta and Delta

• Gene ID URL :

  3043; 3045