BTBD10 Polyclonal Antibody

CAT: 0498-bs-8398RSize: 100 µLDry Ice: NoHazardous: No
CAT#:0498-bs-8398RSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The BTB (broad-complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. BTBD10 (BTB (POZ) domain containing 10), also known as GMRP1, is a ubiquitously expressed nuclear protein found at highest levels in adult testis, brain and small intestine and weakly expressed in colon, lung, liver, kidney, spleen, pancreas, thymus, prostate, heart and ovary. Down-regulated in glioma, BTBD10 binds PP2A (protein phosphatase 2A) to inhibit dephosphorylation of Akts and is suggested to be a suppressor of cell death as well as an enhancer of cell growth. BTBD10 contains one BTB (POZ) domain and is encoded by a gene mapping to human chromosome 11p15.2.
Synonyms
BTB broad complex tramtrack and bric a brac pox virus and zinc finger domain containing protein 10 ; BTB POZ domain containing 10; BTB domain containing 10; BTB/POZ domain-containing protein 10; GMRP 1; GMRP1; K+ channel tetramerization protein; BTBDA_HUMAN.
Gene ID
84280
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Rat
Immunogen
301-400/475
Target
BTBD10
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human BTBD10
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
84280
Predicted Cross Reactivity
Human, Mouse, Dog, Sheep, Pig, Horse, Chicken, Rabbit

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