Products for Research Use Only
RegisterLogin

Ecadherin binding protein E7 Antibody

CAT: 0498-bs-8386RSize: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0498-bs-8386RSize:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
CBLL1, also known as HAKAI (meaning destruction? in Japanese), or RNF188 (RING finger protein 188), is a 491 amino acid protein that contains one C2H2-type zinc finger and one RING-type zinc finger. CBLL1 is believed to function as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfers that residue to a protein that is targeted for degradation. More specifically, upon activation of c-Src, CBLL1 interacts with and ubiquitinates tyrosine-phosphorylated E-cadherin, thereby targeting the E-cadherin complex for endocytosis and disrupting epithelial cell-cell contacts. Via its role as an E-cadherin regulator, CBLL1 participates in cell adhesion and may also be involved in the regulation of epithelial-mesenchymal transitions.
Synonyms
C-Cbl-like protein 1; CasBrM murine ecotropic retroviral transforming sequencelike 1; Casitas B-lineage lymphoma transforming sequence-like protein 1; Casitas B-lineage lymphoma-like 1; Casitas B-lineage lymphoma-transforming sequence-like protein 1; cbll1; E3 ubiquitin-protein ligase Hakai; Ecadherin binding protein E7; FLJ23109; HAKAI; HAKAI_HUMAN; MGC163403; OTTHUMP00000206720; OTTHUMP00000206722; OTTHUMP00000206724; RING finger protein 188; RNF188; MGC163401.
Gene ID
79872
Cellular Locus
Nucleus
Host
Rabbit
Immunogen
221-320/491
Target
Ecadherin binding protein E7
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human CBLL1/Ecadherin binding protein E7
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
79872
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Cow, Pig, Horse

Related Products

CatalogName
bs-0714RHPV16 E7 Polyclonal Antibody
bs-10446R-TRHPV16 E7 Polyclonal Antibody
bs-2969RHPV33 E7 Polyclonal Antibody
bs-10202RHPV16 E7 Polyclonal Antibody
bs-0992RHPV16 E7 Polyclonal Antibody
bs-10446R-01HPV16 E7 Polyclonal Antibody
bs-2969R-PEHPV33 E7 Polyclonal Antibody, PE Conjugated
bs-10202R-Cy5HPV16 E7 Polyclonal Antibody, Cy5 Conjugated
bs-10202R-BiotinHPV16 E7 Polyclonal Antibody, Biotin Conjugated
bs-10202R-APCHPV16 E7 Polyclonal Antibody, APC Conjugated

Alternative Products

CatalogName
MBS9238559-01Ecadherin binding protein E7 Polyclonal Antibody
E47R8386Ecadherin binding protein E7 Rabbit pAb
GTR17730469-01Ecadherin binding protein E7 Rabbit Polyclonal Antibody
SL8386R-01Rabbit Anti-Ecadherin binding protein E7 antibody
GTR18425624Ecadherin binding protein E7 Rabbit Polyclonal Antibody (BF405)
GTR18425602Ecadherin binding protein E7 Rabbit Polyclonal Antibody (BF555)
GTR17755773Ecadherin binding protein E7 Rabbit Polyclonal Antibody (HRP)
GTR17731497Ecadherin binding protein E7 Rabbit Polyclonal Antibody (FITC)
GTR17826511Ecadherin binding protein E7 Rabbit Polyclonal Antibody (Cy7)
GTR18425613Ecadherin binding protein E7 Rabbit Polyclonal Antibody (BF488)

Popular Products