Products for Research Use Only
RegisterLogin

UBE2J2 Polyclonal Antibody

CAT: 0498-bs-8381RSize: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0498-bs-8381RSize:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Ubiquitination is an important molecular mechanism by which abnormal or short-lived proteins are targeted for degradation by the concerted efforts of at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) . UBE2J2 (Ubiquitin-conjugating enzyme E2 J2), also known as NCUBE2 (Non-canonical ubiquitin-conjugating enzyme 2), is a 259 amino acid single pass type IV membrane protein that that belongs to the E2 ubiquitin-conjugating enzyme family and is involved in protein degradation. Localized to the membrane of the endoplasmic reticulum (ER), UBE2J2 catalyzes the attachment of ubiquitin to misfolded membrane proteins, thereby targeting them for proteasomal destruction. This ATP-dependent reaction yields AMP, a diphosphate and a ubiquitin-tagged protein and may be a method of quality control within the ER. Two isoforms of UBE2J2 exist due to alternative splicing events.
Synonyms
NCUBE-2; NCUBE2; Non-canonical ubiquitin-conjugating enzyme 2; UB2J2_HUMAN; UBC6; UBC6 homolog; ube2j2; Ubiquitin-conjugating enzyme E2 J2.
Gene ID
118424
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Human
Immunogen
1-100/259
Target
UBE2J2
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human UBE2J2
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
118424
Predicted Cross Reactivity
Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit

Related Products

CatalogName
bs-8348RUBE2D2 Polyclonal Antibody
bs-8353RUBE2E2 Polyclonal Antibody
bs-8374RUBE2J1 Polyclonal Antibody
bs-8349RUbe2G2 Polyclonal Antibody
bs-8383R-01UBE2Q1 Polyclonal Antibody
bs-8350RUbe2L3 Polyclonal Antibody
bs-24324RUBE2Q1 Polyclonal Antibody
bs-8371RUbe2G1 Polyclonal Antibody
bs-8369RUbe2L6 Polyclonal Antibody
bs-8356RUBE2D1 Polyclonal Antibody

Alternative Products

CatalogName
MBS9127604-01UBE2J2 Polyclonal Antibody
TMAB-13936-01Anti-UBE2J2 Polyclonal Antibody
TA383016UBE2J2 Rabbit Polyclonal Antibody
NBP1-59760Rabbit Polyclonal UBE2J2/UBC6 Antibody
GTR17755770UBE2J2 Rabbit Polyclonal Antibody (HRP)
GTR17770825UBE2J2 Rabbit Polyclonal Antibody (AP)
H00118424-B01PMouse Polyclonal UBE2J2/UBC6 Antibody
70R-1777UBE2J2 antibody

Popular Products