KLHDC9 Polyclonal Antibody

• Background :

  The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. The Kelch domain-containing protein 9 (KLHDC9), also designated Kelch/ankyrin repeat-containing cyclin A1-interacting protein (KARCA1), contains 3 Kelch repeats and interacts with CCNA1. The gene encoding KLHDC9 maps to chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene of human chromosome 1, which encodes lamin A. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

• Synonyms :

  KARCA1; Kelch domain containing 9; Kelch domain containing protein 9; Kelch domain-containing protein 9; Kelch/ankyrin repeat containing cyclin A1 interacting protein; Kelch/ankyrin repeat-containing cyclin A1-interacting protein; KLDC9_HUMAN; Klhdc9; MGC33338; RP11-544M22.9.

• Gene ID :

  126823

• Cellular Locus :

  Cytoplasm, Nucleus

• Host :

  Rabbit

• Cross Reactivity :

  Mouse

• Immunogen :

  221-320/349

• Target :

  KLHDC9

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Conjugation :

  Unconjugated

• Source :

  KLH conjugated synthetic peptide derived from human KLHDC9

• Applications :

  ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

• Purification :

  Purified by Protein A.

• Concentration :

  1µg/µl

• Dilution :

  ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

• Buffer :

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification :

  Unmodified

• Storage Conditions :

  Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

• Gene ID URL :

  126823

• Predicted Cross Reactivity :

  Human, Rat, Dog, Cow, Pig, Horse, Rabbit