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DPP8 Polyclonal Antibody

CAT: 0498-bs-8295RSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0498-bs-8295RSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Dipeptidyl peptidases (DPPs) mediate regulatory activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. DPPs have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. DPPs can bind specific voltage-gated potassium channels and alter their expression and biophysical properties and may also influence T cells. DPP proteins include DPRP1, DPRP2, DPP3, DPP7, DPP10, DPPX and CD26. DPRP1 (dipeptidyl-peptidase IV-related protein 1), also known as DPP8 (dipeptidyl-peptidase 8), DP8 or MSTP141, is a member of the peptidase S9B family of proteins that exhibit prolyl oligopeptidase activity. DPRP1 localizes to the cytoplasm and is ubiquitously expressed with predominant expression in placenta, brain, prostate, testis and muscle. DPRP1 is similar to CD26 (dipeptidyl peptidase IV) suggesting that it may be involved in immune function and participate in the activation of T-cells.
Synonyms
Dipeptidyl peptidase 8; Dipeptidyl peptidase IV-related protein 1; Dipeptidyl peptidase VIII; DP8; DPRP-1; EC 3.4.14.5; Prolyl dipeptidase DPP8; DPP8_HUMAN.
Gene ID
54878
Cellular Locus
Cytoplasm
Host
Rabbit
Immunogen
301-400/898
Target
DPP8
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human DPP8/DPRP1
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
54878
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Cow, Sheep, Pig, Horse

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