COMMD3 Polyclonal Antibody, FITC Conjugated

• Background:

  May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237) . May down-regulate activation of NF-kappa-B (PubMed:15799966) . Modulates Na (+) transport in epithelial cells by regulation of apical cell surface expression of amiloride-sensitive sodium channel (ENaC) subunits (PubMed:23637203) .

• Synonyms:

  BUP; C10orf8; COMM domain-containing protein 3; Protein Bup; Protein PIL; COMMD3

• Gene ID:

  23412

• Swiss Prot:

  Q9UBI1

• Cellular Locus:

  Cytoplasm, Nucleus

• Host:

  Rabbit

• Cross Reactivity:

  Mouse

• Immunogen:

  101-195/195

• Target:

  COMMD3

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Conjugation:

  FITC

• Source:

  KLH conjugated synthetic peptide derived from human COMMD3

• Applications:

  WB, IF (IHC-P), IF (IHC-F), IF (ICC)

• Purification:

  Purified by Protein A.

• Excitation Emission:

  494nm/518nm

• Concentration:

  1µg/µl

• Dilution:

  WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

• Buffer:

  Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification:

  Unmodified

• Storage Conditions:

  Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

• Gene ID URL:

  23412

• Predicted Cross Reactivity:

  Human, Rat, Dog, Cow