ALAD Polyclonal Antibody

CAT: 0498-bs-7954RSize: 100 µLDry Ice: NoHazardous: No
CAT#:0498-bs-7954RSize:100 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.Involvement in disease:Defects in ALAD are the cause of acute hepatic porphyria (AHP) . AHP is a form of porphyria. Porphyrias are inherited defects in the biosynthesis of heme, resulting in the accumulation and increased excretion of porphyrins or porphyrin precursors. They are classified as erythropoietic or hepatic, depending on whether the enzyme deficiency occurs in red blood cells or in the liver. AHP is characterized by attacks of gastrointestinal disturbances, abdominal colic, paralysis, and peripheral neuropathy. Most attacks are precipitated by drugs, alcohol, caloric deprivation, infections, or endocrine factors.
Synonyms
ALAD; ALADH; ALADR; Aminolevulinate dehydratase; Aminolevulinate, delta, dehydratase; Delta aminolevulinic acid dehydratase; Delta-aminolevulinic acid dehydratase; HEM2_HUMAN; Lv; PBGS; Porphobilinogen synthase.
Gene ID
210
Swiss Prot
P13716
Cellular Locus
Cytoplasm, Nucleus, Secreted, Extracellular matrix
Host
Rabbit
Cross Reactivity
Mouse
Immunogen
151-240/330
Target
ALAD
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human ALAD
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
210

Related Products

CatalogName
bs-105408P-01Recombinant Human ALAD Protein, N-His
BSKR65611-01Rat Aminolevulinate Delta Dehydratase (ALAD) ELISA Kit
BSKH63081-01Human Aminolevulinate Delta Dehydratase (ALAD) ELISA Kit
bs-9516RALAS-E Polyclonal Antibody
bs-9516R-Cy7ALAS-E Polyclonal Antibody, Cy7 Conjugated
bs-9516R-PEALAS-E Polyclonal Antibody, PE Conjugated
bs-9516R-RBITCALAS-E Polyclonal Antibody, RBITC Conjugated
bs-9516R-Cy5ALAS-E Polyclonal Antibody, Cy5 Conjugated
bs-9516R-HRPALAS-E Polyclonal Antibody, HRP Conjugated
bs-9516R-APCALAS-E Polyclonal Antibody, APC Conjugated

Alternative Products

CatalogName
27690-01ALAD Polyclonal Antibody
BS71206ALAD polyclonal antibody
TA346146ALAD Rabbit Polyclonal Antibody
NBP1-56507Rabbit Polyclonal ALAD Antibody
MBS9442713-01ALAD Polyclonal Conjugated Antibody

Popular Products