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AIFM2 Polyclonal Antibody

CAT: 0498-bs-7655RSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0498-bs-7655RSize:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Oxidoreductase, which may play a role in mediating a p53/TP53-dependent apoptosis response. Probable oxidoreductase that acts as a caspase-independent mitochondrial effector of apoptotic cell death. Binds to DNA in a sequence-independent manner. May contribute to genotoxin-induced growth arrest.Tissue specificity: Detected in most normal tissues as two transcripts of 1.8 and 4.0 kb in length, respectively. Highly expressed in heart, moderately in liver and skeletal muscles, and expressed at low levels in placenta, lung, kidney, and pancreas. Both transcripts expressed following p53/TP53 induction. The shorter 1.8 kb transcript seems to be the major transcript in EB1 colon cancer cells.
Synonyms
Am2; AM2_HUMAN; AMID; Apoptosis inducing factor A homologous mitochondrion associated inducer of death; Apoptosis inducing factor A like mitochondrion associated inducer of death; Apoptosis inducing factor mitochondrion associated 2; Apoptosis-inducing factor 2; Apoptosis-inducing factor homologous mitochondrion-associated inducer of death; Apoptosis-inducing factor-like mitochondrion-associated inducer of death; Cys51Stop; p53 responsive gene 3 p53 tumor suppressor p53-responsive gene 3 protein PRG3 TRP53 Tumor protein p53.
Gene ID
84883
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Immunogen
121-180/373
Target
AM2
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human AMID/AIFM2
Applications
ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
84883
Predicted Cross Reactivity
Human, Mouse, Rat, Cow, Sheep, Pig

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