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RTN3 Polyclonal Antibody

CAT: 0498-bs-7644RSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0498-bs-7644RSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. There are 5 isoforms.
Synonyms
ASYIP; Neuroendocrine specic protein like 2; NSP like protein II; NSPL2; NSPLII; Reticulon 3; Reticulon3; RTN3_HUMAN.
Gene ID
10313
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Immunogen
931-1032/1032
Target
RTN3
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human NSPL2/RTN3
Applications
ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
10313
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Cow, Pig, Horse

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