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CATSPER3 Polyclonal Antibody

CAT: 0498-bs-7136RSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0498-bs-7136RSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CatSpers (cation channel, sperm associated proteins) are ion transport proteins located on the surface of sperm cells in the principal piece of the sperm tail. CatSpers are vital to sperm motility, fertilization and cAMP-mediated calcium influx in sperm. There are four CatSper proteins in mammalian sperm, namely CatSper (or CatSper1), CatSper2, CatSper3 and CatSper4. CatSper proteins contain a single, six-transmembrane-spanning segment and exhibit the voltage-dependent Ca2+ channel four-repeat structure. CatSper proteins are believed to assemble into a heterotetrameric complex, forming an alkalinization-activated Ca2+-selective channel. Mutations in any of the genes encoding CatSper family proteins can result in male infertility. CatSper3 plays an important role in the hyperactivated motility of sperm cells, a process that is required in the preparation of sperm for fertilization.
Synonyms
Cation channel sperm-associated protein 3; calcium channel repeat containing 1; putative ion channel CatSper3; cav-like protein; one-repeat calcium channel-like protein; CATSPER3; CACRC; Cav-like protein; CACRC; Cation channel, sperm associated 3; CTSR3_HUMAN; putative ion channel CatSper3.
Gene ID
347732
Swiss Prot
Q86XQ3
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Mouse, Rat
Immunogen
201-300/398
Target
CATSPER3
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human CATSPER3
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
347732
Predicted Cross Reactivity
Human, Rabbit

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