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Noxa Polyclonal Antibody

CAT: 0498-bs-7074RSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0498-bs-7074RSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity) . Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.
Synonyms
Adult T cell leukemia derived PMA responsive; APR; APR_HUMAN; Immediate early response protein APR; Immediate-early-response protein APR; Phorbol 12 myristate 13 acetate induced protein 1; Phorbol-12-myristate-13-acetate-induced protein 1; PMA induced protein 1; PMA-induced protein 1; PMAIP1; Protein Noxa.
Gene ID
5366
Cellular Locus
Cytoplasm
Host
Rabbit
Immunogen
21-54/54
Target
Noxa
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human Noxa
Applications
ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
5366
Predicted Cross Reactivity
Human, Mouse, Rat, Pig, Horse

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