Dynamin Antibody

• Background:

  Dynamin is a member of a group of nerve terminal proteins called dephosphins that regulate synaptic vesicle endocytosis (Cousin et al., 2001; Graham et al., 2002; Tsuboi et al., 2002) . There are 3 known isoforms of Dynamin, each having several splice variants as well. Dynamin I is expressed only in neurons whereas Dynamin II is ubiquitously expressed and Dynamin III is found primarily in the testes. Dynamin 1 is phosphorylated by PKC and dephosphorylated by calcineurin.

• Synonyms:

  B dynamin antibody, D100 antibody, DNM 1 antibody, DNM antibody, DNM1 antibody, DYN1_HUMAN antibody, Dynamin antibody, Dynamin-1 antibody, Dynamin1 antibody

• Gene ID:

  1759

• Swiss Prot:

  Q05193

• Host:

  Rabbit

• Cross Reactivity:

  Human, Mouse, Rat

• Target:

  Dynamin

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Conjugation:

  Unconjugated

• Source:

  Synthetic peptide corresponding to amino acid residues from the N-terminal region of human dynamin, conjugated to keyhole limpet hemocyanin (KLH) .

• Applications:

  WB

• Purification:

  Antigen Affinity purification from Pooled whole antiserum

• Concentration:

  Lot Dependent

• Dilution:

  WB (1:300-5000)

• Buffer:

  10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

• Modification:

  Unmodified

• Storage Conditions:

  Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

• Specificity:

  Specific for endogenous levels of the ~95 kDa dynamin protein.

• Gene ID URL:

  1759

• Predicted Cross Reactivity:

  Bovine, Chicken, Non-Human Primate