Products for Research Use Only
RegisterLogin

ATRIP (Ser239) Antibody

CAT: 0498-bs-70024RSize: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0498-bs-70024RSize:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
ATRIP, ATR interacting protein, binds to ATR to regulate ATR expression, and is an essential component of the DNA damage checkpoint pathway (Cortez et al, 2001) . ATR is recruited to DNA lesions in part through its association with ATRIP, which in turn interacts with the single-stranded DNA binding protein RPA (Ball et al, 2007) . DNA replication forks may stall as a result of DNA damage causing phosphorylation of several proteins, including BRCA1 when colocalizing with ATR/ATRIP complex and RPA (Venere et al, 2007) . The DNA replication fork stall coincides with BRCA1 directly phosphorylating ATRIP at Ser-239 (Venere et al, 2007) .
Synonyms
AGS1 antibody, ATIP antibody, ATM and Rad3 related interacting protein antibody, ATM and Rad3-related-interacting protein antibody, ATR interacting protein antibody, ATR-interacting protein antibody, Atrip antibody, ATRIP_HUMAN antibody, DKFZp762J2115 antibody, FLJ12343 antibody, MGC20625 antibody, MGC21482 antibody, MGC26740 antibody
Gene ID
84126
Swiss Prot
Q8WXE1
Modification Site
Ser239
Host
Rabbit
Cross Reactivity
Mouse
Target
ATRIP (Ser239)
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser239 of human ATRIP, conjugated to keyhole limpet hemocyanin (KLH) .
Applications
WB
Purification
Antigen Affinity purification from Pooled whole antiserum
Concentration
Lot Dependent
Dilution
WB (1:300-5000)
Buffer
10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
Modification
Phosphorylation
Storage Conditions
Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
Specificity
Specific for endogenous levels of the ~86 kDa ATRIP protein phosphorylated at Ser239. The antibody also recognizes a band at ~32 kDa.
Gene ID URL
84126
Predicted Cross Reactivity
Human, Bovine, Sheep, Non-Human Primate

Related Products

CatalogName
bsm-62417R-01ATRIP Recombinant Antibody
bsm-62417R-TRATRIP Recombinant Antibody
bs-3466RPhospho-VASP (Ser239) Polyclonal Antibody
bs-11223RATRIP/TREX1 Polyclonal Antibody
bsm-62417R-RBITC-01ATRIP Recombinant Antibody, RBITC Conjugated
bsm-62417R-APC-01ATRIP Recombinant Antibody, APC Conjugated
bsm-62417R-HRP-TRATRIP Recombinant Antibody, HRP Conjugated
bsm-62417R-Cy3-TRATRIP Recombinant Antibody, Cy3 Conjugated
bsm-62417R-FITC-01ATRIP Recombinant Antibody, FITC Conjugated
bsm-62417R-Cy7-01ATRIP Recombinant Antibody, Cy7 Conjugated

Alternative Products

CatalogName
GTR17699957ATRIP (Ser239) Antibody
OAAB11333-400ULATRIP Antibody (Phospho-Ser239)
p116-239Anti-ATRIP (Ser239) Antibody
P03862Anti-Phospho-ATRIP (Ser239) Antibody
NBP2-29537Rabbit Polyclonal ATRIP [p Ser239] Antibody
MBS502187-01Anti-Phospho-Ser239 ATRIP
MBS8552511-01ATRIP (Phospho-Ser239) Rabbit pAb
11158-01VASP (Phospho-Ser239) Antibody
CSB-PA151836Phospho-VASP (Ser239) Antibody
A9683-01VASP (Phospho Ser239) Antibody

Popular Products