CLUAP1 Polyclonal Antibody, Cy7 Conjugated

• Background:

  CLUAP1 (Clusterin associated protein 1) is a 413 amino acid nuclear protein that exists as two alternatively spliced isoforms that interact with Clusterin. CLUAP1 is suggested to play a role in apoptosis and cell proliferation, and is expressed in testis, thrachea and thyroid, with low levels found in adrenal gland and spinal cord. The gene encoding CLUAP1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

• Synonyms:

  Clusterin associated protein 1; FLJ13297; KIAA0643; CLUA1_HUMAN.

• Gene ID:

  23059

• Cellular Locus:

  Nucleus

• Host:

  Rabbit

• Immunogen:

  35-140/413

• Target:

  CLUAP1

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Conjugation:

  Cy7

• Source:

  KLH conjugated synthetic peptide derived from human CLUAP1

• Applications:

  WB, IF (IHC-P), IF (IHC-F), IF (ICC)

• Purification:

  Purified by Protein A.

• Excitation Emission:

  743nm/767nm

• Concentration:

  1µg/µl

• Dilution:

  WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

• Buffer:

  Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification:

  Unmodified

• Storage Conditions:

  Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

• Gene ID URL:

  23059

• Predicted Cross Reactivity:

  Human, Mouse, Rat, Dog, Sheep, Pig, Horse, Chicken, Rabbit