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Desmoglein 1 Polyclonal Antibody

CAT: 0498-bs-6725RSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0498-bs-6725RSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.Defects in DSG1 are the cause of palmoplantar keratoderma striate type 1 (SPPK1) [MIM:148700]; also known as keratosis palmoplantaris striata I. SPPK1 is a dermatoligical disorder characterized by thickening of the skin on the palms and soles, and longitudinal hyperkeratotic lesions on the palms, running the length of each finger.
Synonyms
Cadherin family member 4; CDHF4; Desmoglein-1; Desmosomal Glycoprotein 1; DG1; DGI; DSG; DSG1; DSG1_HUMAN; Pemphigus Foliaceus Antigen; PPKS1; SPPK1.
Gene ID
1828
Cellular Locus
Cell membrane
Host
Rabbit
Immunogen
51-150/1049
Target
Desmoglein 1
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human Desmoglein 1
Applications
ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
1828
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Rabbit

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