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ADAMTS10 Polyclonal Antibody

CAT: 0498-bs-6588RSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0498-bs-6588RSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ADAMTS10 is a member of the ADAMs family of proteinases with Thrombospondin motifs. The catalytic site of ADAMTS10 is typical of the metalloproteinase catalytic domains, with an HExxHxxxxxH sequence, perhaps giving these enzymes some shared specificity. ADAMTS10 is closest in homology to ADAMTS6, sharing 53% overall identity. Functional mutations in ADAMTS10 have been linked to Weill Marchesani syndrome, a connective tissue disorder marked by fibrillin 1 misprocessing. ADAMTS10 has also been reported to be over expressed in breast cancer tissues and cell lines.
Synonyms
A disintegrin and metalloproteinase with thrombospondin mots 10; A disintegrin like and metalloprotease reprolysin type with thrombospondin type 1 mot, 10; ADAM metallopeptidase with thrombospondin type 1 mot 10; ADAM TS10; EC 3.4.24; WMS; ATS10_HUMAN.
Gene ID
81794
Cellular Locus
Secreted, Extracellular matrix
Host
Rabbit
Immunogen
851-950/1103
Target
ADAMTS10
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human ADAMTS10
Applications
ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
81794
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Cow, Sheep, Pig, Rabbit

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