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CDMP1 Polyclonal Antibody

CAT: 0498-bs-6580RSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0498-bs-6580RSize:100 µL
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Background
Defects in GDF5 are the cause of acromesomelic chondrodysplasia Grebe type (AMDG) . Acromesomelic chondrodysplasias are rare hereditary skeletal disorders characterized by short stature, very short limbs, and hand/foot malformations. The severity of limb abnormalities increases from proximal to distal with profoundly affected hands and feet showing brachydactyly and/or rudimentary fingers (knob-like fingers) . AMDG is an autosomal recessive form characterized by normal axial skeletons and missing or fused skeletal elements within the hands and feet.Defects in GDF5 are the cause of acromesomelic chondrodysplasia Hunter-Thompson type (AMDH) . AMDH is an autosomal recessive form of dwarfism. Patients have limb abnormalities, with the middle and distal segments being most affected and the lower limbs more affected than the upper. AMDH is characterized by normal axial skeletons and missing or fused skeletal elements within the hands and feet.Defects in GDF5 are the cause of brachydactyly type C (BDC) . BDC is an autosomal dominant disorder characterized by an abnormal shortness of the fingers and toes.
Synonyms
Cartilage derived morphogenetic protein 1; Cartilage-derived morphogenetic protein 1; CDMP-1; CDMP1; GDF-5; Gdf 5; GDF5_HUMAN; Growth dferentiation factor 5; Growth/dferentiation factor 5; LAP4; Radotermin.
Gene ID
8200
Cellular Locus
Secreted, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse
Immunogen
201-300/501
Target
CDMP1
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human CDMP1/GDF5
Applications
WB, ELISA
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
8200
Predicted Cross Reactivity
Rat, Dog, Cow, Pig, Horse, Rabbit

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