WISP1 Polyclonal Antibody, PerCP Conjugated

• Background:

  Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X (L) protein. Adheres to skin and melanoma fibroblasts. In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan.

• Synonyms:

  CCN4; WISP1c; WISP1i; WISP1tc; WNT1-inducible-signaling pathway protein 1; WISP-1; CCN family member 4; Wnt-1-induced secreted protein; WISP1

• Gene ID:

  8840

• Swiss Prot:

  O95388

• Cellular Locus:

  Secreted

• Host:

  Rabbit

• Immunogen:

  237-295/367

• Target:

  WISP1

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Conjugation:

  PerCP

• Source:

  KLH conjugated synthetic peptide derived from human WISP1

• Applications:

  IF (IHC-P), IF (IHC-F), IF (ICC)

• Purification:

  Purified by Protein A.

• Excitation Emission:

  482nm/677nm

• Concentration:

  1µg/µl

• Dilution:

  IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

• Buffer:

  Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification:

  Unmodified

• Storage Conditions:

  Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

• Gene ID URL:

  8840

• Predicted Cross Reactivity:

  Human, Mouse, Rat, Rabbit